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Updated: May 8, 2026

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
Published on: June 6, 2025
[Liver transplant with donated graft after controlled cardiac death. Current situation]
Manuel Abradelo De Usera1, Carlos Jiménez Romero, Carmelo Loinaz Segurola
1Servicio de Cirugía General, Aparato Digestivo y Trasplante de Organos Abdominales, Hospital Universitario 12 de Octubre, Madrid, España.
Abstract:
An increasing pressure on the liver transplant waiting list, forces us to explore new sources, in order to expand the donor pool. One of the most interesting and with a promising potential, is donation after cardiac death (DCD). Initially, this activity has developed in Spain by means of the Maastricht type II donation in the uncontrolled setting. For different reasons, donation after controlled cardiac death has been reconsidered in our country. The most outstanding circumstance involved in DCD donation is a potential ischemic stress, that could cause severe liver graft cell damage, resulting in an adverse effect on liver transplant results, in terms of complications and outcomes. The complex and particular issues related to DCD Donation will be discussed in this review.
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