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Updated: Aug 13, 2026

Studying DNA Looping by Single-Molecule FRET
Published on: June 28, 2014
[The effect of long-range interactions between adsorbed ligands on the DNA helix-coil transition]
Abstract:
The influence of different types of long-range interaction of ligands adsorbed on DNA on the helix-coil transition was theoretically considered. The contact interaction was shown to differ significantly from the long-rang one. It was shown also that even weak dependence of a long-range potential on a degree of helicity resulted in the strong changes of a DNA melting curve. This result allowed to understand the different experimental data on DNA melting in the presence of different substances which reduced AT-and GC-base pairs thermostability difference.
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