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[Identification of a group A arbovirus isolated in the Far East]
Abstract:
Strains Nos. 296 and 260 isolated from Aedes vexans and Culex pipiens mosquitoes in the USSR Far East in 1971 and 1973, respectively, were identified. The size of the viruses was found to be about 50 nm. Both strains were pathogenic for 2--3-day-old and 3--4-week-old mice by the intracerebral, subcutaneous and intraperitoneal routes, agglutinated goose red blood cells at the optimal pH 6.0. The strains were identical to each other and by their antigenic structure were classified as Semliki Forest virus.
Insights
Two mosquito-borne virus strains from the USSR Far East were identified as Semliki Forest virus. These viruses, approximately 50 nm in size, proved pathogenic in mice and agglutinated goose red blood cells.
Area of Science:
- Virology
- Arbovirology
- Mosquito-borne diseases
Context:
- Mosquitoes (Aedes vexans, Culex pipiens) collected in the USSR Far East in 1971 and 1973.
- Isolation and identification of two distinct virus strains, Nos. 296 and 260.
Purpose:
- To characterize and classify novel virus strains isolated from mosquitoes.
- Determine the pathogenic potential and antigenic properties of the isolated viruses.
Summary:
- Virus strains Nos. 296 and 260, isolated from Aedes vexans and Culex pipiens mosquitoes, were identified as approximately 50 nm in size.
- Both strains demonstrated pathogenicity in mice via multiple inoculation routes (intracerebral, subcutaneous, intraperitoneal).
- Antigenic analysis confirmed the strains' identity as Semliki Forest virus, with optimal hemagglutination of goose red blood cells at pH 6.0.
Impact:
- Contributes to the understanding of arbovirus diversity in the USSR Far East.
- Provides crucial data for potential public health risk assessment and disease surveillance.
- Enhances knowledge of Semliki Forest virus epidemiology and characteristics.