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Topical anesthetic abuse.

G O Rosenwasser1, S Holland, S C Pflugfelder

  • 1Department of Ophthalmology, Milton S. Hershey Medical Center, Hershey, PA 17033.

Ophthalmology
|August 1, 1990
PubMed
Summary
This summary is machine-generated.

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Topical ocular anesthetic abuse can cause severe eye damage, including persistent epithelial defects and corneal issues. It may mimic Acanthamoeba keratitis, necessitating careful diagnosis by eye care practitioners.

Area of Science:

  • Ophthalmology
  • Toxicology

Background:

  • Topical ocular anesthetic abuse is a significant clinical problem.
  • It can lead to severe ocular surface disease, including keratitis and persistent epithelial defects.

Observation:

  • The study observed six individuals with topical ocular anesthetic abuse.
  • Key clinical features included persistent epithelial defects, corneal stromal ring infiltrates, disproportionate pain, and substance abuse.

Findings:

  • Two patients required penetrating keratoplasty for corneal perforation.
  • Two eyes sustained permanent structural damage, and two eyes required enucleation.
  • Five patients were initially misdiagnosed with Acanthamoeba keratitis.

Implications:

Related Experiment Videos

  • Topical ocular anesthetic abuse should be considered in the differential diagnosis of chronic keratitis.
  • It can present similarly to Acanthamoeba keratitis, leading to misdiagnosis.
  • Ophthalmologists should avoid prescribing or dispensing topical anesthetics and minimize opportunities for their theft.