Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

1.6K
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
1.6K
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

1.2K
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
1.2K
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

658
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
658
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

592
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
592
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

478
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
478
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

625
Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
625

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cardiac Surgery-Associated Acute Kidney Injury: Procedure-Specific Incidence and Impact on Mortality-An Algorithm-Based Big Data Fusion Analysis.

Medical sciences (Basel, Switzerland)·2026
Same author

Comparison of Cardiac Troponin T and I: Impact on Definitions of Perioperative Myocardial Infarction After Coronary Artery Bypass Grafting.

Journal of the American Heart Association·2026
Same author

The pioneering era of bilateral internal mammary artery grafting for CABG in Europe.

Frontiers in cardiovascular medicine·2026
Same author

Do Sonication Results of Mobile Parts Predict Failure After Debridement and Implant Retention in Acute Periprosthetic Joint Infection?

Open forum infectious diseases·2026
Same author

Rethinking Aortic Risk: The Potential Impact of Novel, Adjusted, and Combined Aortic Measures in the Prediction of Aortic Dissection.

The Canadian journal of cardiology·2026
Same author

Comparative results of pulmonary vein isolation in atrial fibrillation patients undergoing off-pump <i>vs</i>. on-pump beating-heart coronary artery bypass grafting: a retrospective cohort study.

Cardiovascular diagnosis and therapy·2026

Related Experiment Video

Updated: May 5, 2026

A Closed-chest Model to Induce Transverse Aortic Constriction in Mice
08:10

A Closed-chest Model to Induce Transverse Aortic Constriction in Mice

Published on: April 5, 2018

18.6K

Type A aortic dissection after nonaortic cardiac surgery.

Olaf Stanger1, Thomas Schachner, Brigitta Gahl

  • 1Department of Cardiovascular Surgery, University Hospital Berne (Inselspital), Berne, Switzerland (O.S., B.G., L.E., T.C.); Clinic of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria (T.S.); University Clinic of Cardiac Surgery, Medical University Graz, Graz, Austria (P.O.); Department of Cardiovascular Surgery, Hietzing Hospital, Vienna, Austria (M.T.); Department of Cardiothoracic Surgery, The Liverpool Heart and Chest Hospital, Liverpool, UK (D.H., M.F.); Department of Cardiac Surgery, Vienna Medical University, Vienna, Austria (D.W.); University Cardiovascular Centre Freiburg-Bad Krotzingen, Freiburg, Germany (M.S., B.R.); Department of Histopathology, Royal Brompton and Harefield NHS Foundation Trust, London, UK (M.N.S.); Department of Cardiac Surgery, Oxford University NHS Hospitals, Oxford, UK (M.P.); Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, OH (J.B.); and Department of Cardiothoracic Surgery, Royal Brompton Hospital, London, UK (J.P.).

Circulation
|September 13, 2013
PubMed
Summary

Previous cardiac surgery, especially coronary artery bypass grafting (CABG), increases operative mortality for type A aortic dissection (AAD). Preoperative angiography and managing coronary disease improve outcomes in these high-risk patients.

Keywords:
aortacardiopulmonary bypasshypertensionpathologysurgery

More Related Videos

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

1.4K
Modified Octopus Technique for Thoracoabdominal Aortic Aneurysm
04:56

Modified Octopus Technique for Thoracoabdominal Aortic Aneurysm

Published on: August 1, 2025

660

Related Experiment Videos

Last Updated: May 5, 2026

A Closed-chest Model to Induce Transverse Aortic Constriction in Mice
08:10

A Closed-chest Model to Induce Transverse Aortic Constriction in Mice

Published on: April 5, 2018

18.6K
Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

1.4K
Modified Octopus Technique for Thoracoabdominal Aortic Aneurysm
04:56

Modified Octopus Technique for Thoracoabdominal Aortic Aneurysm

Published on: August 1, 2025

660

Area of Science:

  • Cardiovascular Surgery
  • Aortic Diseases
  • Surgical Outcomes

Background:

  • Cardiac surgery involving cardiopulmonary bypass can lead to type A aortic dissection (AAD) due to aortic manipulation.
  • Pre-existing aortic wall pathology, particularly medial degeneration, contributes to AAD at sites of surgical trauma.

Purpose of the Study:

  • To investigate the impact of prior cardiac surgery, specifically coronary artery bypass grafting (CABG), on operative mortality in patients undergoing repair for type A aortic dissection (AAD).
  • To identify factors influencing outcomes in patients with AAD following previous cardiac surgery.

Main Methods:

  • Retrospective analysis of 103 patients who underwent surgical repair for AAD after nonaortic cardiac surgery.
  • Logistic regression modeling was used to assess the association between prior CABG and operative mortality.
  • Analysis of intimal tear locations, aortic diameters, and histological findings in resected tissues.

Main Results:

  • Patients with prior CABG had significantly higher operative mortality for AAD repair compared to non-CABG patients (OR 2.90).
  • In late AAD cases, mortality was highest in patients lacking preoperative coronary angiography and proper management of coronary/graft disease (OR 5.36).
  • Intimal tears were predominantly at sites of previous surgical trauma, and dissected aortas often showed medial degeneration.

Conclusions:

  • Preexisting aortic pathology, exacerbated by mechanical trauma during cardiac surgery, predisposes to AAD.
  • Prior CABG is a significant risk factor for increased operative mortality in AAD repair.
  • Preoperative coronary angiography and management of coronary/graft disease are crucial for improving outcomes in patients with AAD after CABG.