Renal aspergillosis secondary to renal intrumentation in immunocompetent patient

Area of Science:

• Urology
• Mycology
• Infectious Diseases

Background:

• Primary renal aspergillosis is uncommon, typically affecting immunocompromised individuals.
• Clinical presentation often mimics bacterial pyelonephritis, complicating diagnosis.

Observation:

• A young, non-immunocompromised male developed unilateral renal aspergillosis post-ureteric calculus removal.
• The patient had obstructive uropathy due to a hypoplastic contralateral kidney.

Findings:

• Initial management involved percutaneous nephrostomy and DJ stent removal for renal function preservation.
• Treatment with oral voriconazole for 3 weeks resulted in a positive clinical response.

Implications:

• This case demonstrates that renal aspergillosis can occur in non-immunocompromised hosts.
• Successful management with antifungal therapy (voriconazole) is feasible, even with complex urinary anatomy.