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Carcinoma ex pleomorphic adenoma. Case report.
Shambulingappa Pallagatti1, Soheyl Sheikh, Deepak Gupta
1Department of Oral Medicine and Radiology, M.M. College of Dental Sciences & Research, Mullane, Ambala, Haryana, India.
The New York State Dental Journal
|September 14, 2013
Summary
Carcinoma ex pleomorphic adenoma (CXPA) is a rare malignancy arising from pleomorphic adenoma. Early diagnosis is crucial for better outcomes in this aggressive salivary gland tumor.
Area of Science:
- Oral pathology
- Surgical oncology
Background:
- Carcinoma ex pleomorphic adenoma (CXPA) is a rare, aggressive malignancy.
- It develops in 6% of pleomorphic adenomas, with only 7% in minor salivary glands.
- Malignant transformation risk increases with untreated duration.
Observation:
- Intraoral CXPA commonly affects the palate, followed by the upper lip and buccal mucosa.
- Hard palate CXPA presents as slow-growing, painless swelling, often involving bone.
- Imaging is frequently non-contributory, leading to misdiagnosis.
Findings:
- This report details a rare case of palatal CXPA with subtle clinical and radiological findings.
- The tumor's potential to extend to the parapharyngeal space and cavernous sinus is noted.
Implications:
- Emphasizes the challenge of diagnosing CXPA, particularly with non-specific presentations.
- Highlights the critical need for early diagnosis to improve patient prognosis.
- Underscores the importance of considering CXPA in differential diagnoses of palatal swellings.
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