Early appearance of diffusion-weighted hyperintensities in aphasic status epilepticus. A case report

N Maalouf1, S G Keyrouz

  • 1University of Arkansas for Medical Sciences; Little Rock, Arkansas, USA - maaloufnancy@yahoo.com, nmaalouf@uams.edu.

The Neuroradiology Journal
|September 14, 2013
PubMed

Insights

Aphasic status epilepticus can cause diffusion-weighted imaging (DWI) abnormalities. Cortical DWI hyperintensities may appear shortly after aphasic status epilepticus, as seen in this patient.

Area of Science:

  • Neurology
  • Neuroradiology

Background:

  • Partial status epilepticus typically presents with focal neurological deficits.
  • Global aphasia as the primary symptom of partial status epilepticus is rare.
  • Diffusion-weighted imaging (DWI) abnormalities are common after prolonged seizures.

Purpose of the Study:

  • To report magnetic resonance imaging (MRI) findings in a patient with aphasic status epilepticus.
  • To summarize brain imaging findings in status epilepticus.
  • To discuss the mechanism of DWI abnormalities in this context.

Main Methods:

  • Case report of a patient with aphasic status epilepticus.
  • Review of literature on brain imaging in status epilepticus.
  • Analysis of MRI findings, including DWI and diffusion restriction.

Main Results:

  • The patient's MRI revealed diffusion restriction four hours after symptom onset.
  • Cortical DWI hyperintensities were observed in this case.
  • Literature review confirmed that DWI abnormalities can occur in status epilepticus.

Conclusions:

  • Aphasic status epilepticus can manifest with early cortical DWI hyperintensities.
  • These findings suggest a potential mechanism for diffusion restriction in the brain during epileptic seizures.