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Early appearance of diffusion-weighted hyperintensities in aphasic status epilepticus. A case report
1University of Arkansas for Medical Sciences; Little Rock, Arkansas, USA - maaloufnancy@yahoo.com, nmaalouf@uams.edu.
Abstract:
Partial status epilepticus rarely manifests mainly with global aphasia. It usually results in diffusion-weighted imaging (DWI) abnormalities after prolonged seizures. We discuss the magnetic resonance imaging (MRI) findings in a patient with aphasic status epilepticus. MRI showed diffusion restriction four hours after onset of symptoms. We summarize previously reported brain imaging findings in status epilepticus and discuss the purported mechanism behind these changes. Findings in our patient, similar to few others described in the literature, suggest that cortical DWI hyperintensities can occur shortly following aphasic status epilepticus.
Insights
Aphasic status epilepticus can cause diffusion-weighted imaging (DWI) abnormalities. Cortical DWI hyperintensities may appear shortly after aphasic status epilepticus, as seen in this patient.
Area of Science:
- Neurology
- Neuroradiology
Background:
- Partial status epilepticus typically presents with focal neurological deficits.
- Global aphasia as the primary symptom of partial status epilepticus is rare.
- Diffusion-weighted imaging (DWI) abnormalities are common after prolonged seizures.
Purpose of the Study:
- To report magnetic resonance imaging (MRI) findings in a patient with aphasic status epilepticus.
- To summarize brain imaging findings in status epilepticus.
- To discuss the mechanism of DWI abnormalities in this context.
Main Methods:
- Case report of a patient with aphasic status epilepticus.
- Review of literature on brain imaging in status epilepticus.
- Analysis of MRI findings, including DWI and diffusion restriction.
Main Results:
- The patient's MRI revealed diffusion restriction four hours after symptom onset.
- Cortical DWI hyperintensities were observed in this case.
- Literature review confirmed that DWI abnormalities can occur in status epilepticus.
Conclusions:
- Aphasic status epilepticus can manifest with early cortical DWI hyperintensities.
- These findings suggest a potential mechanism for diffusion restriction in the brain during epileptic seizures.
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