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Updated: May 7, 2026

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity
Published on: April 26, 2012
Oxaliplatin induced-neuropathy in digestive tumors
María Sereno1, Gerardo Gutiérrez-Gutiérrez2, César Gómez-Raposo1
1Medical Oncologist, Medical Oncology Department, Infanta Sofía University Hospital, San Sebastian de los Reyes, Madrid 28702, Spain.
Abstract:
Oxaliplatin is one of the main drugs used in digestive tumors treatment. Peripheral neuropathy is a well-recognized dose-limiting toxicity of OXL. Two types of neuropathy have been described with this agent: acute or transient and chronic or persistent, with different etiology, clinical manifestations and prognosis. This paper is an exhaustive review about the main aspects of oxaliplatin induced peripheral neuropathy, focus in clinical features, treatment, prevention strategies and future approach.
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