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Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
An in vivo model system for evaluation of the host response to biomaterials
Brian Sicari1, Neill Turner, Stephen F Badylak
1Department of Cellular and Molecular Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Methods in Molecular Biology (Clifton, N.J.)
|September 14, 2013
Abstract:
We describe an in vivo model system designed to evaluate the host response to implanted biomaterials: The partial thickness rat abdominal wall defect model. The model allows for determination of the temporal and spatial distribution of the cellular and vascular response, the remodeling of the implanted material and surrounding host soft tissue, and the function of the remodeled tissue over time.
