This study describes a modified octopus technique for endovascular treatment of thoracoabdominal aortic aneurysms, demonstrating favorable clinical...

Source: Hannah L. Cebull1, Arvin H. Soepriatna1, John J. Boyle2 and Craig J. Goergen1
1Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana
2Mechanical Engineering & Materials Science, Washington University in St. Louis, St Louis, Missouri
The mechanical behavior of soft tissues, such as blood vessels, skin, tendons, and other organs, are strongly influenced by their composition of elastin and collagen, which provide elasticity and strength. The fiber...

Source: Arvin H. Soepriatna1, Kelsey A. Bullens2, and Craig J. Goergen1
1 Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana
2 Department of Biochemistry, Purdue University, West Lafayette, Indiana
Near-infrared fluorescence (NIRF) imaging is an exciting optical technique that utilizes fluorescent probes to visualize complex biomolecular assemblies in tissues. NIRF imaging has many advantages over conventional imaging methods for noninvasive imaging of diseases....

This protocol describes a calcium phosphate-induced abdominal aortic aneurysm (AAA) mouse model to study the pathological features and molecular mechanisms of...

This novel model creates robust infrarenal abdominal aortic aneurysms in swine using a combination of balloon angioplasty, elastase/collagenase perfusion, topical elastase application, and oral compound β-aminopropionitrile administration, which interferes with collagen...

Histological and biochemical modifications after aneurysm endograft exclusion are still unclear. We describe a new model of endograft implantation on a murine aneurysm. Through thrombus analysis with and without persistant circulating blood stream interface, and new endovascular biomaterials evaluation, this model will help to better understand endovascular aneurysm exclusion...