Suspected Buruli ulcer of the face: a case report from Ethiopia

David Gordon1, Meseret Zelalem, Gordon E Schutze

  • 1From the *Baylor International Pediatric AIDS Initiative, Houston, TX; †Department of Pediatrics and Child Health, Gondar University Hospital, Gondar, Ethiopia; ‡Department of Pediatric Infectious Disease, Baylor College of Medicine, Houston, TX; and §Department of Dermatovenerology, Gondar University Hospital, Gondar, Ethiopia.

Insights

This study details the non-surgical treatment of a child’s facial Buruli ulcer using rifampin and ciprofloxacin. This approach is novel for facial Buruli ulcer cases, especially in immunocompromised patients.

Area of Science:

  • Infectious Diseases
  • Dermatology
  • Pediatrics

Background:

  • Buruli ulcer is a neglected tropical disease caused by Mycobacterium ulcerans.
  • Facial involvement is rare and challenging to manage.
  • Nonsurgical treatment is preferred when feasible.

Observation:

  • A 14-month-old boy with suspected facial Buruli ulcer was treated.
  • The patient had co-existing conditions: AIDS, presumed tuberculosis, and severe acute malnutrition.
  • Treatment involved rifampin and ciprofloxacin.

Findings:

  • Successful nonsurgical management of facial Buruli ulcer was achieved.
  • The combination of rifampin and ciprofloxacin proved effective.
  • This case highlights a potential alternative to surgery for facial lesions.

Implications:

  • Nonsurgical management may be a viable option for facial Buruli ulcer.
  • This approach could be particularly beneficial for pediatric patients with comorbidities.
  • Further research into nonsurgical protocols for facial Buruli ulcer is warranted.

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