Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Therapeutic Drug Monitoring: Drug Analysis Methods01:26

Therapeutic Drug Monitoring: Drug Analysis Methods

Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood or body tissues to tailor drug therapy effectively. This monitoring is critical for managing drugs with narrow therapeutic indices like digoxin and phenytoin, ensuring they are both safe and effective. For instance, monitoring theophylline levels in asthma patients involves precision and sensitivity to adjust doses according to individual responses to therapy, ensuring efficacy and...
Drug Concentrations: Measurements01:23

Drug Concentrations: Measurements

Drug concentration is the quantity of a drug present in a biological sample. Measuring drug amounts in biological samples allows the clinician to understand how a drug is absorbed, distributed, metabolized, and excreted. Samples can be obtained through invasive or non-invasive methods. Invasive techniques involve surgical or parenteral interventions to gather blood, cerebrospinal fluid, or tissue biopsy. Conversely, non-invasive approaches provide samples like urine, feces, and saliva.
Plasma —...
Preclinical Development: Overview01:28

Preclinical Development: Overview

Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
Drug Discovery: Overview01:26

Drug Discovery: Overview

Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...
Drug Administration and Therapy Phases: Overview01:26

Drug Administration and Therapy Phases: Overview

Drugs, the chemical agents used in diagnosing, treating, or preventing diseases, undergo a four-phase process of development: pharmaceutic, pharmacokinetics, pharmacodynamics, and therapeutic.
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
Drug Regulation01:25

Drug Regulation

Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Precision Medicine in Atopic Dermatitis: Present and Future.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2026
Same author

Atopic dermatitis Yardstick: A new era of topical and systemic treatments.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2026
Same author

The 2025 WAO Guidelines for the classification, diagnosis, and treatment of hereditary angioedema, with consideration of worldwide disparities.

The World Allergy Organization journal·2026
Same author

Global disparities in adrenaline access: A World Allergy Organization call for equity in anaphylaxis care.

The World Allergy Organization journal·2025
Same author

A World Allergy Organization (WAO) manifesto for the worldwide approval of biologic therapies for food allergy.

The World Allergy Organization journal·2025
Same author

Correction: Complete/Near-Complete Itch Response Observed in Patients with Moderate-to-Severe Atopic Dermatitis Initiating Dupilumab: 3-Year, Real-World, Interim Data from the PROSE Registry.

Dermatology and therapy·2025
Same journal

The Toxin of the Year: Airborne PM<sub>2.5</sub>.

Dermatitis : contact, atopic, occupational, drug·2026
Same journal

Eyelid Dermatitis: A 5-Year Retrospective Review from a Metropolitan Contact Dermatitis Clinic.

Dermatitis : contact, atopic, occupational, drug·2026
Same journal

<i>Letter:</i> Anogenital Dermatitis Rarely Occurs in Isolation: Disease Distribution and Delays in Patch Testing.

Dermatitis : contact, atopic, occupational, drug·2026
Same journal

Practical Techniques: Photopatch Testing.

Dermatitis : contact, atopic, occupational, drug·2026
Same journal

Assessment and Clinical Management of Patients With Atopic Dermatitis Undergoing Patch Testing: Recommendations From an International Electronic Delphi Consensus.

Dermatitis : contact, atopic, occupational, drug·2026
Same journal

Digital Image Superimposition for Identifying Delayed Patch Test Reactions: A Clinical Pearl.

Dermatitis : contact, atopic, occupational, drug·2026
See all related articles

Related Experiment Video

Updated: May 7, 2026

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones
06:06

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones

Published on: February 5, 2018

Patch testing for drugs.

Marcella Rita Aquino1, Janelle Sher, Luz Fonacier

  • 1From the *State University of New York at Stony Brook, Stony Brook; and †Winthrop Rheumatology, Allergy & Immunology, Mineola, NY.

Dermatitis : Contact, Atopic, Occupational, Drug
|September 14, 2013
PubMed
Summary
This summary is machine-generated.

Drug patch testing aids in diagnosing skin reactions to medications. This review examines its use for various drug classes and provides guidance on clinical application and contraindications.

More Related Videos

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
10:17

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

Validated LC-MS/MS Panel for Quantifying 11 Drug-Resistant TB Medications in Small Hair Samples
08:54

Validated LC-MS/MS Panel for Quantifying 11 Drug-Resistant TB Medications in Small Hair Samples

Published on: May 19, 2020

Related Experiment Videos

Last Updated: May 7, 2026

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones
06:06

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones

Published on: February 5, 2018

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
10:17

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

Validated LC-MS/MS Panel for Quantifying 11 Drug-Resistant TB Medications in Small Hair Samples
08:54

Validated LC-MS/MS Panel for Quantifying 11 Drug-Resistant TB Medications in Small Hair Samples

Published on: May 19, 2020

Area of Science:

  • Dermatology
  • Clinical Pharmacology
  • Immunology

Background:

  • Adverse drug reactions (ADRs) frequently cause diverse cutaneous eruptions.
  • Drug patch testing is increasingly utilized for diagnosing specific drug-induced skin conditions.
  • A standardized methodology for drug patch testing is currently lacking.

Purpose of the Study:

  • To review the current literature on the evidence of patch testing for drugs.
  • To address the application of patch testing for specific cutaneous adverse drug reactions.
  • To examine the use of patch testing for drug classes like antimicrobials, anticonvulsants, antiretrovirals, glucocorticoids, and NSAIDs.

Main Methods:

  • A comprehensive review of existing literature was conducted.
  • Evidence regarding patch testing for specific drug eruptions was systematically evaluated.
  • Clinical approaches and contraindications for drug patch testing were analyzed.

Main Results:

  • The review covers the diagnostic utility of patch testing for various drug-induced skin reactions.
  • Evidence for patch testing in specific drug classes, including antimicrobials and NSAIDs, is discussed.
  • Guidance on performing drug patch testing in clinical settings and identifying contraindications is provided.

Conclusions:

  • Drug patch testing is a valuable diagnostic tool for cutaneous adverse drug reactions.
  • Standardization of drug patch testing methodology is needed for wider adoption.
  • This review offers a framework for the clinical application of drug patch testing.