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Updated: May 7, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Predictors of persistent sleep apnea after surgery in children younger than 3 years
Insights
Obstructive sleep apnea (OSA) often persists in children under three after adenotonsillectomy (T&A). Preoperative OSA severity is a key predictor of residual disease, suggesting postoperative polysomnography may be needed.
Area of Science:
- Pediatric Otolaryngology
- Sleep Medicine
- Pediatric Pulmonology
Background:
- Obstructive sleep apnea (OSA) is a prevalent condition in children, potentially leading to significant health issues.
- Predictors for persistent OSA following adenotonsillectomy (T&A) in young children remain understudied.
Purpose of the Study:
- To assess residual OSA in children under three years old post-T&A.
- To identify predictors of persistent OSA after T&A in this age group.
Main Methods:
- Retrospective review of medical records at a tertiary children's hospital.
- Inclusion of children under three with documented OSA via polysomnogram (PSG) who underwent T&A.
- Analysis of preoperative and postoperative PSG data for 70 patients.
Main Results:
- T&A demonstrated significant improvements in apnea-hypopnea index (AHI), baseline and minimum oxygen saturation, and sleep efficiency.
- Twenty-one percent of patients exhibited residual OSA (AHI > 5) after T&A.
- The severity of preoperative OSA, determined by PSG, was the most consistent predictor of residual disease.
Conclusions:
- A substantial rate of residual OSA was observed in children under three years old following T&A.
- Preoperative OSA severity is a critical factor in predicting postoperative residual disease.
- Postoperative PSG evaluation may be warranted for these young patients.
Importance:
Obstructive sleep apnea (OSA) is a common disorder in children and can lead to important sequelae. Predictors of persistent OSA after adenotonsillectomy (T&A) in younger children are not well studied.
Objective:
To evaluate residual OSA in a subgroup of children younger than 3 years after T&A and identify predictors of postoperative residual disease. DESIGN, SETTING, AND PARTICIPANTS Retrospective review of medical records at a tertiary academic children's hospital involving children younger than 3 years who had OSA documented by polysomnogram(PSG) and underwent T&A during the period October 1, 2002, through June 30, 2010. Some of these children had both preoperative and postoperative PSGs. MAIN OUTCOMES AND MEASURES Effect of T&A on sleep study parameters and predictors of persistent disease after surgery. RESULTS A total of 283 patients (mean [SD] age, 22 [7] months) underwent a preoperative PSG, with 70 of these patients having both a preoperative and postoperative PSG. In the group who had preoperative and postoperative PSGs, there were statistically significant improvements in mean (SD) apnea hypopnea index (AHI) (34.8 [40.7] to 5.7 [13.8]; P < .001), baseline oxygen saturation (96.6%[2.1%] to 97.2%[1.4%]; P = .05), minimum oxygen saturation (77.2%[11.4%] to 89.9%[6.8%]; P < .001), and sleep efficiency (84.7%[14.9%] to 88.7%[9.1%]; P = .02) after T&A. When AHI greater than 5 was used as the definition of OSA, 21% of the patients (15 of 70) had residual OSA. The most consistent predictor of residual OSA after T&A was the severity of preoperative OSA (P = .02). CONCLUSIONS AND RELEVANCE In a subgroup of children younger than 3 years with OSA, we found a high rate of residual OSA after T&A. Predictors of residual disease include severity of preoperative OSA as determined by PSG result. Postoperative PSGs might be indicated in these patients.
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