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Updated: May 7, 2026

11:27
Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
Published on: December 4, 2016
Hybrid assemblies based on a gadolinium-containing polyoxometalate and a cationic polymer with spermine side chains
Wenqiang Chai1, Shan Wang, Hang Zhao
1Institute of Physical Chemistry, University of Mainz, Jakob-Welder Weg 11, 55099 Mainz (Germany).
Chemistry (Weinheim an Der Bergstrasse, Germany)
|September 14, 2013
Abstract:
Supramolecular assembly: Spherical and stable hybrid assemblies based on a cationic polymer with spermine side chains and an anionic Gd(3+)-containing polyoxometalate cluster (GdW) are prepared by electrostatic interaction. The T1-weighted MRI performance of GdW is enhanced about three times in the assemblies; meanwhile, the assemblies show good biocompatibility, which enables them to be promising candidates for MRI contrast agents.

