Surgical treatment for severe heart failure: recent progress in treatment strategy and its present status in Japan
1Division of Organ Regeneration Surgery, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8504, Japan.
Insights
For severe heart failure unresponsive to medication, surgical options like left ventriculoplasty and ventricular assist devices are crucial alternatives to heart transplantation due to donor limitations.
Area of Science:
- Cardiology
- Cardiac Surgery
- Medical Technology
Background:
- Chronic intractable heart failure, often caused by ischemic cardiomyopathy (ICM) or dilated cardiomyopathy (DCM), severely impairs left ventricular function.
- Current treatments for advanced heart failure include heart transplantation, but donor scarcity limits its widespread application.
- Alternative surgical interventions are essential for managing patients with severe left ventricular hypofunction.
Purpose of the Study:
- To provide an overview of current surgical treatments for severe heart failure.
- To discuss left ventriculoplasty, heart transplantation, and ventricular assist devices (VADs).
- To highlight recent advancements in VAD technology for heart failure management.
Main Methods:
- Review of current literature and clinical practices regarding surgical interventions for heart failure.
- Analysis of the efficacy and limitations of left ventriculoplasty, heart transplantation, and VADs.
- Discussion of the evolving landscape of mechanical circulatory support.
Main Results:
- Heart transplantation remains a primary option but is limited by donor availability.
- Left ventriculoplasty offers a surgical alternative for specific heart failure etiologies.
- Ventricular assist devices have demonstrated significant progress and improved outcomes in managing advanced heart failure.
Conclusions:
- Surgical interventions, including left ventriculoplasty and VADs, are vital for patients with end-stage heart failure unresponsive to medical therapy.
- Advancements in VAD technology are expanding treatment options and improving quality of life for heart failure patients.
- A multi-faceted approach combining medical, surgical, and device-based therapies is necessary for optimal heart failure management.
Abstract:
Chronic intractable heart failure that is unresponsive to maximum medical therapy can have a wide variety of causes; these include advanced valvular diseases and severe myocardial ischemia, ischemic cardiomyopathy (ICM) in heart failure following extensive myocardial infarction, chronic heart failure due to dilated cardiomyopathy (DCM) in which the myocardium itself is progressively damaged or the acute aggravation of the latter. Heart transplantation has long been considered the only useful treatment for patients with heart failure due to ICM- and DCM-induced severe left ventricular hypofunction. However, because of the extremely limited number of heart transplant donors, other surgical treatments have also been attempted. In this communication, we provide an overview of the current situation with regard to left ventriculoplasty and heart transplantations, as well as of the treatment of severe heart failure using ventricular assist devices, which have recently shown remarkable progress.
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