In vitro antimicrobial susceptibility of staphylococci isolated from canine pyoderma in Rio de Janeiro, Brazil

Area of Science:

• Veterinary Dermatology
• Microbiology
• Antimicrobial Resistance

Background:

• Canine pyoderma is a common bacterial skin infection in dogs.
• Staphylococci are frequently implicated pathogens in canine pyoderma.
• Rising antimicrobial resistance poses a therapeutic challenge.

Purpose of the Study:

• To investigate the etiological agents of staphylococci in canine pyoderma.
• To determine the antimicrobial resistance patterns of these isolates.
• To identify effective antimicrobial agents for treating canine pyoderma.

Main Methods:

• Samples were collected from dogs diagnosed with pyoderma.
• Staphylococcal isolates were identified using standard biochemical tests.
• Antimicrobial susceptibility testing was performed against 15 different antimicrobials.

Main Results:

• Thirty-nine staphylococcal isolates were obtained.
• Staphylococcus pseudintermedius was the most prevalent species (47.4%).
• All isolates exhibited resistance to at least one antimicrobial.
• A high prevalence of multidrug resistance (77.1%) was observed.
• Oxacillin demonstrated the highest efficacy against the tested isolates.

Conclusions:

• Staphylococcus species, especially S. pseudintermedius, are key pathogens in canine pyoderma.
• There is a high and concerning level of antimicrobial resistance, including multidrug resistance, among these isolates.
• Oxacillin may be a valuable therapeutic option, but further research is needed.