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Related Experiment Video

Updated: May 7, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

Hemispheric lateralization interrupted: material-specific memory deficits in temporal lobe epilepsy.

Kim Celone Willment¹, Alexandra Golby

¹Department of Neurology, Brigham and Women's Hospital , Boston, MA , USA ; Department of Psychiatry, Brigham and Women's Hospital , Boston, MA , USA ; Golby Lab, A Surgical Brain Mapping Laboratory, Department of Neurosurgery, Brigham and Women's Hospital , Boston, MA , USA.

Frontiers in Human Neuroscience

|September 14, 2013

Summary

This summary is machine-generated.

Patients with medial temporal lobe epilepsy (mTLE) reveal how memory is lateralized in the brain. Research shows left and right temporal lobes handle different memory types, aiding clinical applications.

Keywords:

fMRI hemispheric lateralization material-specific memory temporal lobe epilepsy

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Published on: August 15, 2025

Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice

Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice

Published on: July 31, 2019

Area of Science:

Neuroscience
Cognitive Psychology
Neurology

Background:

Hemispheric lateralization of memory is primarily studied in patients with medial temporal lobe epilepsy (mTLE).
The material-specific model posits left temporal lobe for verbal memory and right for non-verbal memory.

Purpose of the Study:

To review key findings in mTLE literature advancing the understanding of material-specific memory deficits.
To explore the clinical translation of functional neuroimaging in mTLE for preoperative memory mapping.

Main Methods:

Review of neuropsychological and neuroimaging literature concerning mTLE.
Analysis of functional neuroimaging patterns related to memory lateralization.

Main Results:

mTLE studies have significantly refined and challenged the traditional material-specific model of memory.
Functional neuroimaging data are increasingly used for preoperative memory mapping in mTLE patients.

Conclusions:

Understanding memory lateralization in mTLE offers insights into brain function.
Preoperative fMRI memory mapping is a promising clinical application derived from mTLE research.