Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Growing bilateral occipital calcifications and epilepsy.

P DeMarco¹, G Lorenzin

¹Centro Angeli Custodi, Istituti Ospedalieri, Trento, Italy.

Brain & Development

|January 1, 1990

Summary

Atypical Sturge-Weber disease cases show growing bilateral occipital calcifications. Despite progression, pediatric patients remain well with controlled seizures and stable EEGs, suggesting a potentially better prognosis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Correlation between tcdB gene PCR cycle threshold and severe Clostridium difficile disease.

Anaerobe·2019

Same author

Typical levels of airborne fungal spores in houses without obvious moisture problems during a rainy season in Florida, USA.

Journal of investigational allergology & clinical immunology·2008

Same author

Allopurinol as add-on therapy in refractory epilepsy: a double-blind placebo-controlled randomized study.

Epilepsia·1994

Same author

The offset V modification of the Chevron bunionectomy: a retrospective study.

The Journal of foot surgery·1992

Same author

Full-spectrum cone sensitivity functions for X-chromosome-linked anomalous trichromats.

Journal of the Optical Society of America. A, Optics and image science·1992

Same author

Tuberous sclerosis, agenesis of the corpus callosum and Lennox-Gastaut syndrome: mere chance or a new syndrome?

Clinical EEG (electroencephalography)·1992

Area of Science:

Neurology
Pediatric Neurology
Neuroimaging

Background:

Increasing cases of bilateral occipital calcifications with epilepsy/migraine are observed.
These cases are often linked to atypical Sturge-Weber disease variants lacking facial nevus flammeus.

Observation:

Two pediatric patients with bilateral occipital calcifications and neurological symptoms were studied.
Patients exhibited typical cortico-subcortical bilateral occipital growing calcifications, despite electroclinical variations.

Findings:

Unlike typical presentations, these patients have remained clinically well.
Seizures are effectively managed with anti-epileptic drugs (AEDs).
Electroencephalogram (EEG) results have remained stable, showing no worsening despite calcification growth.

Implications:

This suggests a potentially more favorable prognosis for certain pediatric cases of Sturge-Weber disease.
Further research is needed to understand the long-term outcomes and management of these atypical presentations.
Findings challenge the generally accepted view of progressive worsening in Sturge-Weber syndrome.

Related Experiment Videos