Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Practical application of oxygen transport principles.

¹Intensive Care Unit, University Hospital of South Manchester, UK.

Critical Care Medicine

|January 1, 1990

Summary

Optimizing oxygen delivery and consumption is key in shock management, not just blood pressure. Individualized patient assessment is crucial, as some treatments may hinder oxygen transport.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Quantifying Recruitment Source and Participant Communication Preferences for Alzheimer's Disease Prevention Research.

The journal of prevention of Alzheimer's disease·2021

Same author

Ricebase: a breeding and genetics platform for rice, integrating individual molecular markers, pedigrees and whole-genome-based data.

Database : the journal of biological databases and curation·2016

Same author

Relationship of ECMO duration with outcomes after pediatric cardiac surgery: a multi-institutional analysis.

Minerva anestesiologica·2014

Same author

Giant increase in the metal-enhanced fluorescence of organic molecules in nanoporous alumina templates and large molecule-specific red/blue-shift of the fluorescence peak.

Nano letters·2014

Same author

Cognitive speed of processing and functional declines in older cancer survivors: an analysis of data from the ACTIVE trial.

European journal of cancer care·2009

Same author

Motor sequence chunking is impaired by basal ganglia stroke.

Neurobiology of learning and memory·2009

Area of Science:

Critical care medicine
Physiology

Background:

Shock management traditionally relies on hemodynamic data.
The ultimate goal of shock therapy is to optimize oxygen delivery (DO2) and consumption (VO2).

Purpose of the Study:

To evaluate the current approach to shock management.
To emphasize the importance of individualized DO2 and VO2 optimization over generalized hemodynamic targets.

Main Methods:

Review of existing data on shock management and oxygen transport.
Analysis of the impact of common interventions on DO2 and VO2.

Main Results:

No single critical threshold for DO2 below which tissue hypoxia occurs was identified.
Interventions like catecholamines and mechanical ventilation with PEEP can negatively impact DO2.
Hemodynamic data alone are insufficient for guiding shock therapy.

Conclusions:

Shock management requires a patient-specific approach focusing on optimizing oxygen delivery and consumption.
Clinicians should avoid relying solely on hemodynamic parameters and prioritize interventions that enhance tissue oxygenation.

Related Experiment Videos