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A feasibility study using TomoDirect for craniospinal irradiation.

Ulrich W Langner¹, Janelle A Molloy, John F Gleason

¹University of Kentucky. ulrich.langner@uky.edu.

Journal of Applied Clinical Medical Physics

|September 17, 2013

Summary

TomoDirect enables craniospinal irradiation (CSI) delivery with potential benefits over helical Tomotherapy, including reduced normal tissue dose. While not superior to 3D CRT, it offers improved patient positioning and efficiency.

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Area of Science:

Radiation Oncology
Medical Physics

Background:

Craniospinal irradiation (CSI) is a complex radiotherapy technique.
Optimizing dose distribution and patient positioning for CSI remains a challenge.

Purpose of the Study:

To investigate the feasibility and dosimetric characteristics of delivering CSI using TomoDirect.
To compare TomoDirect plans with helical Tomotherapy and 3D conformal therapy (3D CRT).

Main Methods:

A method for generating TomoDirect plans with field junctioning was developed.
TomoDirect plans were compared to helical Tomotherapy and 3D CRT plans for CSI.

Main Results:

TomoDirect plans may reduce low dose to normal tissues compared to helical Tomotherapy.

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TomoDirect offers advantages in patient positioning (supine) and setup simplicity over 3D CRT.

Treatment times for TomoDirect were comparable to 3D CRT and shorter than helical Tomotherapy.

Conclusions:

TomoDirect is a feasible technique for CSI delivery.
TomoDirect presents potential advantages in normal tissue sparing and treatment efficiency.
Further investigation into planning parameters for TomoDirect CSI is warranted.