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Updated: May 7, 2026

A Pre-clinical Rat Model for the Study of Ischemia-reperfusion Injury in Reconstructive Microsurgery
Published on: November 8, 2019
Stomal recurrence: salvage surgery and reconstruction utilizing microvascular free tissue transfer
Amy Pittman1, Robert Lindau, Peter Andersen
1Department of Otolaryngology, Head and Neck Surgery, Loyola University Medical Center, Maywood, IL.
Background:
Stomal recurrence in patients after laryngectomy has a poor prognosis. Studies performed using sternal resection with pectoralis flap reconstruction report <25% 2-year survival. The purpose of this study was to ascertain whether the use of larger resection with free flap reconstruction improves survival.
Methods:
Thirteen cases of stomal recurrence that underwent extended sternal resection and free flap reconstruction were identified and classified according to Sisson criteria. Postoperative morbidity, mortality, and survival were assessed.
Results:
Median survival was 10 months in patients with Sisson types I and II, with 37.5% 1-year and 25% 2-year survival. Median survival was 6 months in patients with Sisson types III and IV, with 40% 1-year and 0% 2-year survival. There were 2 perioperative deaths and a major morbidity rate of 45%.
Conclusion:
Salvage surgery using free flap reconstruction did not show improved survival rates compared with previously described techniques.