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Related Experiment Video

Updated: May 7, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
05:47

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

A framework for understanding medical epistemologies.

George Khushf1

  • 1*Department of Philosophy, University of South Carolina, Columbia, SC 29208, USA. khushf@sc.edu.

The Journal of Medicine and Philosophy
|September 17, 2013
PubMed
Summary

Medical epistemology examines how healthcare professionals gain and use knowledge through epistemic practices. This study proposes a new framework viewing epistemology as a practice aimed at mitigating errors in knowledge development and application.

Keywords:
clinical reasoningepistemologyerrorevidence-based medicine

Related Experiment Videos

Last Updated: May 7, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
05:47

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

Area of Science:

  • Medical epistemology
  • Philosophy of science
  • Social sciences of medicine

Background:

  • Understanding how clinicians and scientists acquire and utilize knowledge is crucial in healthcare.
  • Epistemic practices, encompassing knowledge production and use, are studied across various disciplines.

Purpose of the Study:

  • To develop a unifying framework for diverse contributions to medical epistemology.
  • To analyze existing frameworks and their limitations in situating medical knowledge production and use.

Main Methods:

  • Survey of existing literature in medical epistemology, philosophy of science, and social sciences of medicine.
  • Critical analysis of three proposed frameworks for medical epistemology.
  • Development of a novel fourth framework for medical epistemology.

Main Results:

  • Identified diverse knowledge claims with distinct uses and justification logics.
  • Highlighted difficulties in establishing a comprehensive framework for medical epistemology.
  • Proposed a new framework conceptualizing epistemology as a practice for error mitigation.

Conclusions:

  • A unified framework is needed to integrate diverse perspectives on medical epistemology.
  • The proposed fourth framework views epistemology as a practice that advances knowledge by addressing errors.
  • This approach parallels medicine's advancement of health by mitigating disease.