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Effect of a Pholiota adiposa Extract on Fat Mass in Hyperlipidemic Mice
Soo-Muk Cho1, Young-Min Lee, Dae-Hyoung Lee
1Rural Resources Development Institute, National Institute of Agricultural Science and Technology, Suwon 441-853, Korea.
Abstract:
The purpose of this study was to investigate the effect of a Pholiota adiposa extract on fat mass in hyperlipidemic mice fed on a high-fat diet. The water extracts from P. adiposa (ASI 24018) were not affected in the total triglyceride contents and epididymal fat mass in mice fed on a high-fat diet, but the retroperitoneal fat mass decreased significantly. This result suggests that the P. adiposa extract may be a potential candidate for use as a functional food that can act as a prophylactic against hyperlipidemia. However, the P. adiposa extract showed no effect in the total triglyceride contents and epididymal fat mass.

