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Related Experiment Video

Updated: May 7, 2026

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation

Published on: August 26, 2014

Capsule endoscopy: a dangerous but diagnostic tool.

Rhatica Srai¹, Lucinda Tullie, Ashar Wadoodi

¹Eastbourne District General Hospital, Eastbourne, East Sussex, UK.

BMJ Case Reports

|September 18, 2013

Summary

Capsule endoscopy (CE) is recommended for obscure GI bleeding when other methods fail. However, this case highlights a rare risk of small bowel obstruction and perforation, even in non-stricturing conditions.

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Last Updated: May 7, 2026

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation

Published on: August 26, 2014

Area of Science:

Gastroenterology
Endoscopy
Surgical Oncology

Background:

Capsule endoscopy (CE) is a valuable diagnostic tool for obscure gastrointestinal bleeding when standard upper and lower endoscopy are inconclusive.
CE is indicated for diagnosing conditions like celiac disease, polyposis, and small bowel tumors.
CE is contraindicated in patients with suspected or known bowel obstruction due to retention risks.

Observation:

A patient presented with obscure gastrointestinal bleeding.
Capsule endoscopy was performed after negative gastroscopy and colonoscopy.
The patient developed small bowel obstruction and perforation.

Findings:

The obstruction and perforation occurred in a segment of small bowel inflamed secondary to a carcinoid tumor.
This complication arose despite the absence of pre-existing luminal compromise typical for contraindications like Crohn's disease.
The case underscores a rare but serious adverse event associated with capsule endoscopy.

Implications:

This case highlights a critical, albeit rare, risk of capsule endoscopy in specific inflammatory conditions.
Clinicians must carefully consider potential risks, even in the absence of typical contraindications.
Further research may be needed to refine risk stratification for capsule endoscopy in complex cases.