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Updated: May 7, 2026
04:48
Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery
Published on: November 28, 2018
Left ventricular noncompaction in patients with bicuspid aortic valve
Anushree Agarwal1, Bijoy K Khandheria, Timothy E Paterick
1Aurora Cardiovascular Services, Aurora Sinai/Aurora St. Luke's Medical Centers, University of Wisconsin School of Medicine and Public Health, Milwaukee, Wisconsin.
Summary
Bicuspid aortic valve (BAV) and left ventricular noncompaction (LVNC) co-occur in 11% of BAV patients. This study characterized the clinical and imaging features of this combined cardiac anomaly in a retrospective echocardiographic analysis.
Area of Science:
- Cardiology
- Medical Imaging
- Genetics
Background:
- Left ventricular noncompaction (LVNC) is typically linked to complex congenital heart defects.
- The association between LVNC and bicuspid aortic valve (BAV), a common anomaly, is poorly documented.
Purpose of the Study:
- To determine the incidence of LVNC in patients with BAV.
- To describe the clinical and echocardiographic characteristics of patients with both BAV and LVNC.
Main Methods:
- Retrospective analysis of an echocardiography database from July 2011 to March 2013.
- Identification of 109 patients with BAV and subsequent evaluation for concomitant LVNC.
Main Results:
- 11.0% (12/109) of BAV patients met criteria for LVNC.
- The average age at diagnosis was 33 years, with a male predominance (9/12).
- Common findings included BAV with right/left cusp fusion, mild/moderate aortic valve dysfunction, and apical LVNC.
Conclusions:
- BAV and LVNC coexist in approximately 11% of BAV patients.
- Further research is required to elucidate the underlying genetic and pathophysiological mechanisms of this association.
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