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Related Concept Videos

Decreased Body Temperature01:29

Decreased Body Temperature

A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by sustained extreme cold exposure, and severe...

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Related Experiment Video

Updated: May 7, 2026

Establishment of Deep Hypothermic Circulatory Arrest in Rats
08:39

Establishment of Deep Hypothermic Circulatory Arrest in Rats

Published on: December 16, 2022

Deep hypothermic circulatory arrest effectively preserves neurocognitive function.

Katherine H Chau1, Tamir Friedman, Maryann Tranquilli

  • 1Section of Cardiothoracic Surgery, Yale University School of Medicine, New Haven, Connecticut.

The Annals of Thoracic Surgery
|September 19, 2013
PubMed
Summary
This summary is machine-generated.

Deep hypothermic circulatory arrest (DHCA) did not significantly impact neurocognitive function compared to standard care in aortic surgery patients. This method, even up to 40 minutes, appears safe for preserving brain function.

Keywords:
26

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Last Updated: May 7, 2026

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05:00

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Area of Science:

  • Cardiovascular Surgery
  • Neuroscience
  • Cognitive Function

Background:

  • Quantitative assessment of neurocognitive effects from deep hypothermic circulatory arrest (DHCA) is limited and conflicting.
  • This study quantitatively assesses neurocognitive function before and after DHCA in comparison to non-DHCA patients.

Purpose of the Study:

  • To quantitatively evaluate the neurocognitive effects of deep hypothermic circulatory arrest (DHCA) in aortic surgery.
  • To compare neurocognitive outcomes between patients undergoing DHCA and those who do not.

Main Methods:

  • Sixty-two aortic surgery patients underwent pre- and post-operative neuropsychometric testing.
  • Tests evaluated memory, processing speed, executive function, and global cognition.
  • Neurocognitive deficit was defined as >20% decline in ≥2 cognitive areas; comparisons were made between DHCA and non-DHCA groups.

Main Results:

  • No significant differences in neurocognitive function or deficit incidence were found between DHCA and non-DHCA groups.
  • No correlation existed between DHCA duration and neurocognitive deficit.
  • Both groups showed memory decline; recognition was also affected in the DHCA group.

Conclusions:

  • Cardiac surgery impacts memory, but overall neurocognitive function is preserved and similar between DHCA and non-DHCA patients.
  • DHCA up to 40 minutes is neurocognitively safe.
  • Straight DHCA effectively preserves neurocognitive function in aortic surgery.