Related Experiment Video
Updated: May 7, 2026

Procedures for In Vitro Cultivation of Treponema pallidum, the Syphilis Spirochete
Published on: January 24, 2025
Oral syphilis: a series of 5 cases
Moritz Hertel1, Daniel Matter2, Andrea M Schmidt-Westhausen3
1Resident, Charité Centre 3, Department of Oral Medicine, Dental Radiology, and Oral Surgery, Charité Medical University Berlin, Berlin, Germany.
Abstract:
Syphilis is an infectious, usually sexually transmitted, disease caused by Treponema pallidum, subspecies pallidum. Because of the increasing prevalence in Europe during the past few years, dentists could be confronted with patients with oral manifestations of syphilis. Because oral lesions are highly contagious, it is vital to make the correct diagnosis quickly to initiate the proper therapy and to interrupt the chain of infection. We present the cases of 5 patients with syphilis-related oral lesions. These cases are representative because of their clinical presentation, age, and gender distribution and the diagnostic approach. The aim of the present report is to emphasize the importance of the dentist knowing and identifying syphilis in different stages to diagnose the disease and institute treatment at an early stage.
Related Concept Videos
Sexually Transmitted Infections
Bacterial Phylum Spirochaetes
Endocarditis II: Clinical Features of Infective Endocarditis
Infectious Diseases and Their Occurrence
Stages of Infection
Endocarditis I: Introduction
