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Updated: May 7, 2026

Bioelectric Analyses of an Osseointegrated Intelligent Implant Design System for Amputees
Published on: July 15, 2009
Osseointegration in the elderly
1Azienda Ospedaliera San Gerardo, Università degli Studi di Milano-Bicocca, Via Pergolesi, 33, 20900, Monza, Italy, giorgio.piarulli@gmail.com.
Abstract:
Osseointegration is a term that refers to the formation of a direct interface between an implant and bone without intervening soft tissue. Cementless femoral fixation in total hip arthroplasty is dependent on mechanical and biological factors that affect implant stability and long-term outcome. Osteoporosis leads to morphological and biological alterations in the proximal femur that adversely affect both mechanical stability of implant and biological response of bone, making it more challenging to achieve a valid osseointegration.
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