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Social Defeat Stress Model for Adolescent C57BL/6 Male and Female Mice

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[Adolescent binge drinking: neurocognitive consequences and gender differences].

L Amrani¹, L De Backer, G Dom

¹Centrum Geestelijke Gezondheidszong Andante.

Tijdschrift Voor Psychiatrie

|September 19, 2013

Summary

This summary is machine-generated.

Binge drinking negatively impacts adolescent and young adult neurocognition, especially executive function and memory. Females show greater susceptibility to spatial working memory and impulse control deficits from binge drinking.

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Area of Science:

Neuroscience
Psychology
Public Health

Context:

Adolescent and young adult binge drinking is increasing.
Neurocognitive effects and gender differences are subjects of ongoing research.
Previous findings on binge drinking's neurocognitive impact have been inconsistent.

Purpose:

To synthesize evidence on binge drinking's adverse neurocognitive effects in adolescents and young adults.
To investigate potential gender-specific differences in these neurocognitive effects.

Summary:

A review of 19 studies indicates significant negative impacts of binge drinking on neurocognition.
Executive functioning and memory are particularly affected.
Eleven studies explored the interaction between binge drinking and gender.

Impact:

Binge drinking detrimentally affects adolescent and young adult neurocognitive functioning.
Females appear more vulnerable to deficits in spatial working memory and impulse control compared to males.
Findings highlight the need for gender-informed interventions for adolescent and young adult alcohol misuse.