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Updated: May 7, 2026

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
(E)-1-(2-Amino-phen-yl)-3-(thio-phen-2-yl)prop-2-en-1-one
Suchada Chantrapromma1, Pumsak Ruanwas, Nawong Boonnak
1Department of Chemistry, Faculty of Science, Prince of Songkla University, Hat-Yai, Songkhla 90112, Thailand.
Abstract:
The mol-ecule of the title heteroaryl chalcone derivative, C13H11NOS, exists in a trans-configuaration and is almost planar with a dihedral angle of 3.73 (8)° between the phenyl and thio-phene rings. An intra-molecular N-H⋯O hydrogen bond generates an S(6) ring motif. In the crystal, two adjacent mol-ecules are linked into a dimer in an anti-parallel face-to-face manner by a pair of C-H⋯O inter-actions. Neighboring dimers are further linked into chains along the c-axis direction by N-H⋯N hydrogen bonds.
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