Related Experiment Video
Updated: May 7, 2026

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
Published on: January 31, 2025
Screening for osteopenia and osteoporosis in an urban community in India
V Silvanus1, K Ghosal, A Behera
1Department of Preventive and Social Medicine, Terna Medical College, Nerul, Navi Mumbai, India. silvanus.v@gmail.com
Abstract:
Osteoporosis is a disease characterized by reduction in the bone mass and disruption of bone architecture leading to impaired skeletal strength and an increased susceptibility of fractures. It is a major public health problem associated with substantial morbidity and socio-economic burden worldwide. The present study was planned to screen bone status of adults over 20 years (when peak bone mass is formed) utilizing calcaneal quantitative ultrasound (QUS) (Hologic Sahara 0058 USG) as a diagnostic tool. A screening camp was conducted in the 1st week of February 2008 at the Terna Hospital and Research Centre along with the Orthopedic Department. A questionnaire was administered to all the screened individuals which included socio-demographic data, assessment of susceptibility to osteoporosis and dietary habits. The bone mineral density (BMD) was measured at the calcaneus by QUS and T-scores were calculated based on WHO criteria. The study yielded a prevalence of 41.4% among women and 33.33% among men for Osteopenia and 12.85% among women 3.7% among men for Osteoporosis respectively. The mean age of the screened sample was 44.25 years. The mean weight, height and body mass index was 56.95 kg, 157.47 cms and 23.047 respectively. The mean bone density was -0.749. A total of 97 individuals screened; of which 70 (72.1%) were females and 27 (27.9%) were males. There was a significant trend of decreasing bone density with an increase in age. Age had an influence on the outcome of osteopenic and osteoporosis score in present study. The subjects with low bone mineral density (BMD) were advised to undergo a Dual energy X-ray absorptiometry (DEXA) scan in order to confirm the diagnosis. The US Preventive Services Task Force recommends routine screening for Osteoporosis in women over 65 years. In India we need to carry out further studies on whether we need to consider screening at an earlier age and also to study osteoporosis in males.
Related Concept Videos
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Osteoclasts in Bone Remodeling
Study Designs in Epidemiology
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and case-control studies.
Essential Minerals for Bone Health
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...