A new triterpenoid saponin from the root of Croton lachnocarpus Benth
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Published on: August 16, 2018
Zheng-Hong Pan1, De-Sheng Ning, Jin-Lei Liu
1a Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization, Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences , Guilin , 541006 , P.R. China.
Abstract:
A new triterpenoid saponin, 3-O-β-D-xylopyranosyl spathodic acid (1), was isolated from the EtOH extract of the root of Croton lachnocarpus Benth., together with four known compounds. These compounds were characterised on the basis of their spectral data and compatible with values in the literature. Compound 1 was the first triterpenoid glucoside isolated from the genus Croton. The known compound myriaboric acid (2) showed cytotoxic activity against human hepatocellular carcinoma SMMC-7721 cell line with an IC50 value of 42.2 μM.
