Electrocardiographic abnormalities and elevated cTNT at admission for intracerebral hemorrhage: predictors for

Clara Hjalmarsson1, Lennart Bergfeldt, Lena Bokemark

  • 1Stroke Unit, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden.

Insights

Electrocardiogram (ECG) abnormalities are common in patients with non-traumatic intracerebral hemorrhage (ICH). Prolonged QTc interval on ECG is an independent predictor of poor survival after ICH, while cardiac troponin levels are not.

Area of Science:

  • Neurology
  • Cardiology
  • Critical Care Medicine

Background:

  • Cerebrovascular lesions, specifically intracerebral hemorrhage (ICH), are frequently linked to electrocardiographic (ECG) abnormalities.
  • Assessing prognostic markers in ICH patients is crucial for patient management and outcomes.

Purpose of the Study:

  • To determine the prognostic significance of ECG abnormalities and elevated cardiac troponin (cTNT) on admission in patients with nontraumatic ICH.
  • To identify specific ECG markers that predict mortality in ICH survivors.

Main Methods:

  • A cohort of 97 consecutive patients with nontraumatic ICH was analyzed.
  • Cox proportional hazard models were employed to evaluate the predictive value of ECG findings and cTNT levels on survival.

Main Results:

  • The most common ECG abnormalities observed were Q waves (39.6%) and prolonged QTc interval (>0.44 s; 35.4%).
  • A prolonged QTc interval was identified as an independent predictor of long-term mortality (P = 0.019).
  • Elevated cTNT levels at admission did not demonstrate prognostic value for survival.

Conclusions:

  • ECG changes are prevalent in patients with ICH.
  • Prolonged QTc interval is a significant independent predictor of poor survival following ICH, highlighting its clinical importance.
Abstract