Related Experiment Video
Updated: May 7, 2026

Staphylococcus aureus Growth using Human Hemoglobin as an Iron Source
Published on: February 7, 2013
Coagulase-negative staphylococci in an HIV-infected child causing pancytopaenia
1Pediatric HIV Clinic, B.J. Wadia Hospital for Children, Mumbai, India.
Abstract:
Although coagulase-negative staphylococci (CONS) constitute normal flora of the human body, some species can produce human infections, particularly when the host defense is breached. There is little evidence of the pathogenicity of CONS in HIV-infected individuals. We present the case of a 14-year-old HIV-infected boy who presented with a right lower zone pneumonia and a cutaneous abscess, following which he developed pancytopaenia due to underlying CONS infection that responded to antibiotic treatment.
Insights
Coagulase-negative staphylococci (CONS) can cause infections in immunocompromised individuals. This case highlights CONS-induced pancytopenia in an HIV-infected adolescent, successfully treated with antibiotics.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Immunocompromised Host Research
Background:
- Coagulase-negative staphylococci (CONS) are common human flora.
- CONS infections typically occur when host defenses are compromised.
- Limited data exists on CONS pathogenicity in individuals with HIV.
Observation:
- A 14-year-old boy with HIV presented with pneumonia and a skin abscess.
- The patient subsequently developed pancytopenia.
- The pancytopenia was attributed to an underlying CONS infection.
Findings:
- The patient's pancytopenia resolved following antibiotic therapy.
- This case demonstrates a rare complication of CONS infection in an HIV-positive adolescent.
- Successful antibiotic treatment was achieved.
Implications:
- Highlights the potential for CONS to cause severe infections in HIV-infected patients.
- Suggests careful monitoring for hematological complications in such cases.
- Reinforces the importance of appropriate antibiotic selection for CONS infections.
Related Concept Videos
Immunodeficiency Diseases
There are three main causes of immunodeficiency disorders...
Staphylococcal Skin Infections
Sexually Transmitted Infections
Cytomegalovirus Disease
