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Updated: May 7, 2026

Synthesis of Indoxyl-glycosides for Detection of Glycosidase Activities
Published on: May 27, 2015
Click reactions as a key step for an efficient and selective synthesis of D-xylose-based ILs
Nadège Ferlin1, Sylvain Gatard, Albert Nguyen Van Nhien
1Institut de Chimie Moléculaire de Reims, UMR CNRS 6229, Université de Reims Champagne-Ardenne, Boîte 44, B.P. 1039, Reims F-51687, France. sandrine.bouquillon@univ-reims.fr.
Abstract:
D-Xylose-based ionic liquids have been prepared from D-xylose following a five steps reaction sequence, the key step being a click cycloaddition. These ionic liquids (ILs) have been characterized through classical analytical methods (IR, NMR, mass spectroscopy, elemental analysis) and their stability constants, Tg and Tdec, were also determined. Considering their properties and their hydrophilicity, these compounds could be alternative solvents for chemical applications under mild conditions.
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