The multiple oral presentations of multiple myeloma
Richard C Cardoso1, Peter J Gerngross, Theresa M Hofstede
1Section of Oral Oncology, Department of Head and Neck Surgery, The University of Texas-M.D. Anderson Cancer Center, Houston, USA.
Summary
Oral manifestations of multiple myeloma can be varied and may signal disease relapse. Early detection through oral cavity examination is crucial for timely diagnosis and treatment of this plasma cell cancer.
Area of Science:
- Hematology
- Oral Medicine
- Oncology
Background:
- Multiple myeloma is a plasma cell malignancy.
- Oral manifestations can be an early sign of disease progression or relapse.
Observation:
- A case series of five patients presented with oral manifestations of multiple myeloma.
- Oral lesions were the initial indicator of disease relapse in these patients.
Findings:
- The oral presentation of multiple myeloma is variable.
- Myeloma lesions in the mouth can mimic common dental pathologies, potentially delaying diagnosis.
Implications:
- Dentists and oncologists must be aware of the diverse oral signs of multiple myeloma.
- Thorough oral examination and prompt biopsy are essential to prevent misdiagnosis and treatment delays.
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