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Studies on the Anti-Inflammatory Effect of Xiaoyao Pills in The Treatment of Postmenopausal Osteoporosis in Mice
Published on: August 23, 2024
New therapeutical horizons in the management of postmenopausal osteoporosis
Silvia Migliaccio1, Rachele Fornari, Emanuela A Greco
1Endocrinology Unit, Department of Movement, Human and Health Sciences, University of "Foro Italico", Largo de Bosis 14, 00135, Rome, Italy, migliacciosilvia@hotmail.it.
Abstract:
Osteoporosis is a bone metabolic disease characterized by a compromised skeletal fragility, leading to an increased risk of developing spontaneous and traumatic fractures. This disease is the consequence of an imbalance of the physiological process of bone turnover (or coupling), with the lost of the equilibrium between the activity of osteoblasts and osteoclasts. Therapy has been aimed mainly at the correction of the imbalance between bone resorption and bone formation, to protect skeletal integrity and reduce the risk of fractures. Thus, pharmacological treatments have been aimed at modulating the activity of bone cells.
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