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Related Concept Videos

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Chronic Obstructive Pulmonary Disease II: Emphysema01:23

Chronic Obstructive Pulmonary Disease II: Emphysema

Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.
Chronic Obstructive Pulmonary Disease I: Introduction01:23

Chronic Obstructive Pulmonary Disease I: Introduction

Chronic obstructive pulmonary disease is a common, preventable, and treatable respiratory disorder characterized by persistent symptoms and progressive airflow limitation. This limitation results from a combination of small-airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), both driven by chronic inflammation from exposure to harmful particles or gases.The disease includes two main pathological entities: emphysema, marked by destruction of alveolar walls and...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...

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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

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Published on: November 4, 2010

Plastic bronchitis in beta thalassemia minor.

Makaresh Yadav1, Sneha Tirpude, Jyotsna M Joshi

  • 1Department of Pulmonary Medicine, T. N. Medical College, B. Y. L. Nair Hospital, Mumbai, India.

Lung India : Official Organ of Indian Chest Society
|September 20, 2013
PubMed
Summary

Plastic bronchitis, a rare lung disorder, involves casting of the bronchial tree. This case highlights its occurrence in a beta-thalassemia minor patient, expanding understanding of this condition.

Keywords:
Beta thalassemia minorbronchial castsplastic bronchitis

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Area of Science:

  • Pulmonary Medicine
  • Hematology

Background:

  • Plastic bronchitis is a rare pulmonary disorder characterized by the formation and expectoration of bronchial casts.
  • It is associated with conditions such as cystic fibrosis, asthma, and pulmonary infections.

Purpose of the Study:

  • To report a unique case of plastic bronchitis in a patient with beta-thalassemia minor.
  • To contribute to the understanding of the diverse etiologies of plastic bronchitis.

Main Methods:

  • Case report of a 33-year-old woman.
  • Clinical presentation and diagnostic findings were reviewed.

Main Results:

  • The patient, diagnosed with beta-thalassemia minor, developed symptoms consistent with plastic bronchitis.
  • Expectoration of bronchial casts was a key clinical feature.

Conclusions:

  • Beta-thalassemia minor may be an underrecognized association with plastic bronchitis.
  • This case broadens the spectrum of conditions linked to plastic bronchitis, emphasizing the need for comprehensive patient evaluation.