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Updated: May 7, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Percutaneous stent-in-stent placement for renal artery stenosis of a solitary functioning kidney
A V Venu Gopal1, M Bhaskar Rao, K Damodar Rao
1Department of Nephrology, Queen's NRI Hospital, Gurudwara Lane, Seethammadhara, Visakhapatnam, Andhra Pradesh, India.
Insights
Renal artery stenosis in young adults can cause hypertension and is treatable with stenting. A rare complication, in-stent thrombosis, was successfully managed with a novel stent-in-stent procedure in a patient with a solitary kidney.
Area of Science:
- Cardiovascular Medicine
- Nephrology
- Interventional Radiology
Background:
- Renal artery stenosis (RAS) is a significant cause of secondary hypertension, particularly in younger populations.
- Endovascular interventions, including stenting, offer effective treatment for RAS.
- In-stent thrombosis (IST) is a rare but serious complication following renal artery stenting.
Observation:
- A young patient presented with IST in a renal artery stent.
- The patient had a solitary functioning kidney, increasing the complexity of management.
- This case highlights the challenges of managing IST in a critical anatomical setting.
Findings:
- Successful treatment of IST was achieved using a stent-in-stent placement technique.
- This approach restored renal artery patency and preserved kidney function.
- The case demonstrates the feasibility of a less invasive salvage option for IST.
Implications:
- Stent-in-stent placement is a viable option for managing IST, especially in complex cases.
- Close follow-up of patients with renal artery stents is crucial for early detection of complications like IST.
- This case expands treatment strategies for a rare but potentially devastating complication of renal artery stenting.
Abstract:
Renal artery stenosis is an important cause of secondary hypertension in young, which can be treated effectively with endovascular interventions including stenting. In-stent thrombosis is an infrequent complication and necessitates the need to follow-up these patients with renal artery stents. We present here a young individual who presented with in-stent thrombosis in a solitary functioning kidney and was successfully treated with stent-in-stent placement.
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