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Updated: May 7, 2026

Preclinical Model of Hind Limb Ischemia in Diabetic Rabbits

Preclinical Model of Hind Limb Ischemia in Diabetic Rabbits

Published on: June 2, 2019

[Diabetic muscle infarction].

Edske ter Bals¹, Henk-Jan van der Woude, Yves F C Smets

¹Onze Lieve Vrouwe Gasthuis, Amsterdam.

Nederlands Tijdschrift Voor Geneeskunde

|September 21, 2013

Summary

Diabetic muscle infarction is a rare diabetes complication. Diagnosis relies on clinical signs and MRI, with treatment involving rest and pain relief.

Area of Science:

Endocrinology
Diabetology
Musculoskeletal Medicine

Background:

Diabetic muscle infarction (DMI) is a rare complication of diabetes mellitus.
Microvascular abnormalities are hypothesized to contribute to DMI pathogenesis.
DMI commonly affects the thigh musculature.

Observation:

A 32-year-old female with a 22-year history of type 1 diabetes presented with acute thigh pain and swelling.
Diagnostic workup included ultrasound, MRI, and biopsy, excluding deep venous thrombosis and abscess.
MRI and clinical presentation confirmed the diagnosis of diabetic muscle infarction.

Findings:

Diabetic muscle infarction diagnosis is established through clinical presentation and MRI.
Muscle biopsy, while performed, was deemed unnecessary for diagnosis in this case.

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Treatment involved conservative measures: bed rest and analgesics.

Implications:

This case highlights the diagnostic utility of MRI in diabetic muscle infarction.
Non-invasive diagnostic methods are crucial for timely DMI management.
Conservative treatment with rest and analgesics is effective for DMI.