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Updated: May 7, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
A novel diiminopyridine ligand containing redox active Co(III) mixed sandwich complexes
Eleanor Magdzinski1, Pierangelo Gobbo, Mark S Workentin
1Department of Chemistry and The Centre for Advanced Materials and Biomaterials Research (CAMBR), The University of Western Ontario , 1151 Richmond Street, London, Ontario N6A 5B7, Canada.
Abstract:
The synthesis of a diiminopyridine (DIMPY) ligand containing pendant mixed sandwich cobaltocene functionalities on the imine nitrogens was prepared and characterized (18). Its reactivity with 2 equiv of GeCl2·dioxane and SnCl2 in THF yields the respective Lewis base mediated autoionization products (18Ge and 18Sn). Analogous low-valent complexes utilizing an N,N'- differocenyl diiminopyridine support were also prepared (15Ge and 15Sn). All compounds were characterized by spectroscopic and X-ray crystallographic methods. Electrochemical studies were conducted for both 15Sn and the precursor of 18.
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