Multicentric chondrosarcomas associated with Ollier's disease. Review and case report

The malignant transformation of enchondromas in patients with Ollier's Disease is a well known occurrence although few studies have prospectively followed patients with this disease and reviewed the frequency of this process. When malignant degeneration occurs, usually only one focus is noted even though others potentially may be involved. This paper represents a case report in which two separate locations of chondrosarcoma were found. Discussion includes chondrosarcomatous transformation of enchondromas, radiographic findings in this transformation, and treatment of multicentric chondrosarcomas in a patient with Ollier's Disease.