Related Experiment Video

Updated: May 7, 2026

Transient Middle Cerebral Artery Occlusion Model of Stroke
05:32

Transient Middle Cerebral Artery Occlusion Model of Stroke

Published on: August 11, 2023

Acute proximal left anterior descending artery occlusion with de Winter sign

Fuad Samadov1, Dursun Akaslan1, Altug Cincin1

  • 1Department of Cardiology, Marmara University, Istanbul, Turkey.

The American Journal of Emergency Medicine
|September 21, 2013
PubMed

Insights

Prompt recognition of acute coronary occlusion via electrocardiography is crucial. This case highlights atypical ECG findings in a patient with confirmed acute thrombotic occlusion, posing diagnostic challenges.

Area of Science:

  • Cardiology
  • Medical Diagnostics
  • Emergency Medicine

Background:

  • Timely recognition of acute coronary occlusion is critical for reperfusion therapy.
  • Standard electrocardiographic (ECG) signs include ST-segment elevation or new left bundle-branch block.
  • Atypical ECG presentations can delay diagnosis and treatment.

Observation:

  • A 41-year-old male presented with symptoms suggestive of acute coronary syndrome.
  • The patient exhibited unusual electrocardiographic (ECG) changes not typical for acute coronary occlusion.
  • Coronary angiography revealed acute thrombotic occlusion of the proximal left anterior descending artery.

Findings:

  • The patient's electrocardiogram (ECG) did not show classic signs of acute coronary occlusion.
  • Despite atypical ECG findings, the diagnosis of acute thrombotic occlusion was confirmed.
  • This case underscores the variability of ECG manifestations in acute coronary events.

Implications:

  • Clinicians must consider atypical ECG findings in the context of acute coronary occlusion.
  • Early diagnosis may require a high index of suspicion beyond standard ECG criteria.
  • Recognizing unusual ECG patterns is vital for initiating prompt reperfusion therapy in acute myocardial infarction.

More Related Videos

Myocardial Infarction and Functional Outcome Assessment in Pigs12:03

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

Related Concept Videos

Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...