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Related Concept Videos

Decreased Body Temperature01:29

Decreased Body Temperature

A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by sustained extreme cold exposure, and severe...
Increased Body Temperature01:25

Increased Body Temperature

A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.
Homeostatic Imbalances in Body Temperature01:19

Homeostatic Imbalances in Body Temperature

Hyperthermia occurs when the body's temperature becomes unusually high, often due to heat exposure, intense physical activity, or certain illnesses. This condition can create a dangerous cycle where elevated body temperature increases the metabolic rate, generating more heat and potentially leading to organ failure and brain damage. A severe form of hyperthermia, called heat stroke, can raise body temperature to life-threatening levels. Fever, on the other hand, is a controlled form of...
Methods of reducing fever01:22

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Factors Affecting Body Temperature01:28

Factors Affecting Body Temperature

As a nurse, it is vital to understand the factors affecting body temperature to monitor variations and effectively evaluate deviations from regular.
Factors may  include:
Thermosensation01:43

Thermosensation

Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...

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Related Experiment Video

Updated: May 7, 2026

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms
05:00

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms

Published on: March 3, 2021

What about temperature? Haloperidol-induced hypotermia.

Maria Salvina Signorelli1, Federico Nalis, Mariacatena Battiato

  • 1Department of Clinical and Molecular Biomedicine, University of Catania, Catania, Italy.

BMJ Case Reports
|September 21, 2013
PubMed
Summary

Antipsychotic drugs like haloperidol can cause hypothermia, a rare adverse reaction. This study documents three human cases of haloperidol-induced hypothermia, highlighting potential risks in clinical practice.

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Last Updated: May 7, 2026

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms
05:00

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms

Published on: March 3, 2021

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
06:43

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
08:22

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model

Published on: October 27, 2020

Area of Science:

  • Neuroscience
  • Pharmacology
  • Clinical Medicine

Background:

  • Antipsychotic medications aim to balance symptom control with adverse reactions.
  • Dopamine D2 receptor activation is hypothesized to cause hypothermia.
  • Haloperidol and other antipsychotics may induce hypothermia in animals.

Observation:

  • Evidence suggests haloperidol and drugs like reserpine and chlorpromazine can induce hypothermia.
  • While some studies limit this to animals, others suggest human occurrence.
  • This report details three rare cases of haloperidol-induced hypothermia in patients.

Findings:

  • Administration of haloperidol resulted in hypothermia in three human patients.
  • This adverse reaction, though rarely documented, occurred following haloperidol treatment.
  • The cases highlight a potential, albeit infrequent, clinical side effect of haloperidol.

Implications:

  • Clinicians should be aware of the potential for haloperidol to induce hypothermia in humans.
  • Monitoring body temperature may be crucial in patients receiving haloperidol.
  • Further research is needed to understand the mechanisms and prevalence of this adverse reaction.