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Related Experiment Video

Updated: May 7, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

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Published on: December 6, 2016

Time-dependent changes in the obstruction pattern during drug-induced sleep endoscopy.

Sung Jae Heo1, Chang Mook Park, Jung Soo Kim

  • 1Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyungpook National University, Daegu, Korea.

American Journal of Otolaryngology
|September 21, 2013
PubMed
Summary

Drug-induced sleep endoscopy (DISE) findings can change during the procedure. Longer DISE durations reveal more obstruction sites and configurations, potentially explaining study discrepancies.

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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

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07:33

Noninvasive, High-throughput Determination of Sleep Duration in Rodents

Published on: April 18, 2018

Area of Science:

  • Otolaryngology
  • Sleep Medicine
  • Respiratory Medicine

Background:

  • Drug-induced sleep endoscopy (DISE) is crucial for diagnosing obstructive sleep apnea (OSA).
  • Previous studies show varied DISE findings, with new obstruction patterns emerging postoperatively.
  • Understanding dynamic changes in airway obstruction during DISE is essential.

Purpose of the Study:

  • To investigate the dynamic changes in obstructive patterns during Drug-induced sleep endoscopy (DISE).
  • To identify how obstruction sites and configurations evolve over the duration of the DISE procedure.

Main Methods:

  • Forty-two patients with OSA underwent a 25-minute DISE.
  • Obstruction sites (velum, oropharynx, tongue base, epiglottis) and velum configurations (anteroposterior, lateral, concentric) were assessed.
  • Changes in obstruction patterns were analyzed over time.

Main Results:

  • Obstructive patterns changed in 33% of patients.
  • Obstruction site changes occurred in 21.4%, and velum configuration changes in 11.9%.
  • Longer DISE duration (over 15 min) significantly increased multiple-level obstructions and revealed more configurations.

Conclusions:

  • DISE findings can be dynamic and change over the procedure duration.
  • Short DISE procedures may miss critical obstruction sites, contributing to study variability.
  • Optimizing DISE duration is important for accurate OSA diagnosis.