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Related Experiment Video

Updated: May 7, 2026

A Swine Model of Neonatal Asphyxia
10:36

A Swine Model of Neonatal Asphyxia

Published on: October 11, 2011

[Neonatal asphyxia: neurologic outcome].

A Allemand1, M Stanca, M Sposato

  • 1Dipartimento di Pediatria e Neuropsichiatria Infantile, Università di Roma "La Sapienza", Roma, Italia - federico.allemand@uniroma1.it.

Minerva Pediatrica
|September 21, 2013
PubMed
Summary
This summary is machine-generated.

Neonatal asphyxia can lead to cerebral palsy (CP) and psychomotor delay. Term infants with adequate weight are more prone to CP with epilepsy, while preterm VLBW infants risk psychomotor delay. Clinical signs at birth predict CP severity.

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Last Updated: May 7, 2026

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10:36

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Published on: October 11, 2011

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19:15

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07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

Area of Science:

  • Neonatology
  • Pediatric Neurology
  • Developmental Pediatrics

Context:

  • Neonatal asphyxia is a significant contributor to infant morbidity and mortality.
  • Understanding long-term neurological outcomes is crucial for timely intervention.

Purpose:

  • To assess the correlation between neonatal variables and neurological outcomes at two years in infants with asphyxia.
  • To establish accurate prognoses and guide targeted therapies for affected infants.

Summary:

  • This study analyzed 63 infants with suspected neonatal asphyxia, tracking clinical and instrumental parameters for two years.
  • Cerebral palsy (CP) and psychomotor delay were common outcomes, with CP associated with epilepsy in 17 infants. Term infants with adequate weight were more likely to develop CP with epilepsy, while preterm VLBW infants showed a higher risk of psychomotor delay.
  • Severe neonatal neurological symptoms and pathological EEG findings were strongly linked to CP severity and early-onset epilepsy.

Impact:

  • Findings aid in predicting neurological sequelae in infants with neonatal asphyxia.
  • Identifies high-risk populations (e.g., preterm VLBW infants) for targeted developmental support.
  • Informs clinical management strategies for optimizing therapeutic interventions and improving long-term outcomes.