Strategy of coping with end-stage disease and cancer-related fatigue in terminally ill patients
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Updated: May 7, 2026

Evaluating the Role of Mitochondrial Function in Cancer-related Fatigue
Published on: May 17, 2018
Aleksandra Modlińska1, Bożena Kowalik2, Tomasz Buss3
1Department of Palliative Medicine, Medical University of Gdańsk, Gdansk, Poland aleksandra.modlinska@gumed.edu.pl.
Unlabelled:
The aim was to investigate whether there is a relationship between strategy of coping with end-stage disease and cancer-related fatigue. The study was conducted using the Rotterdam Symptom Checklist, Brief Fatigue Inventory, and Mini-Mental Adjustment to Cancer scale to specify patient's strategy of coping. Finally, 51 hospice care patients with cancer were analyzed.
Main Findings:
The majority of responders adopted 1 of the 2 styles; avoidance (belongs to adaptive coping) or anxious preoccupation (destructive or maladaptive). Less often moderate fatalism and helpless/hopeless (H/H) or fighting spirit were observed. Significant correlation has been found between H/H or fatalism strategy and fatigue.
Conclusions:
High level of fatigue had a negative impact on almost all aspects of daily living among people with H/H or fatalism strategy.
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