The outcome of triplet gestations complicated by fetal death

Intrauterine death in twin pregnancies has been reported to be associated with a very high incidence of morbidity and mortality in the surviving co-twin, mostly attributed to vascular disruption when vascular anastomosis exists between the twins' circulations. The present study describes the obstetric, neonatal, and follow-up data of five triplet gestations complicated by intrauterine death of one or two fetuses, compared with a control group of triplets matched for gestational age. Delivery occurred an average of 30 +/- 26 days after the diagnosis of intrauterine fetal death. Four of the five placentas were monochorionic. All nine infants survived, but four were small for gestational age (SGA). A comparison of study cases and controls revealed that monochorionic placentation was found only in the study group, that SGA infants were more likely (but not significantly so) to be in the study group, and that study infants required significantly less ventilatory support. Although the only case of long-term morbidity was in the study group, the cause of this complication was consistent with prematurity.