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Prevalence and risk factors for resistant hypertension among hypertensive patients from a developing country

W A Nuwan Kumara1, Thisara Perera, Mekhala Dissanayake

  • 1Department of Pharmacology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka. priyanga.ranasinghe@gmail.com.

BMC Research Notes
|September 24, 2013
PubMed

Insights

Resistant hypertension affects nearly one-fifth of South Asian hypertensive patients, with obesity and diabetes mellitus being key risk factors. Understanding these factors is crucial for managing uncontrolled blood pressure.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Public Health

Background:

  • Investigating the prevalence and risk factors of resistant hypertension (RHT) in a South Asian hypertensive cohort.
  • Addressing the need for specific risk factor identification in diverse ethnic populations.

Purpose of the Study:

  • To determine the prevalence of resistant hypertension.
  • To identify differential risk factors associated with resistant hypertension in South Asian patients.

Main Methods:

  • A descriptive cross-sectional study involving 277 hypertensive patients at a cardiology clinic.
  • Data collected via interviewer-administered questionnaires.
  • Binary logistic regression analysis to identify significant co-variants associated with RHT.

Main Results:

  • 41.1% of patients had uncontrolled blood pressure, with 19.1% having resistant hypertension.
  • Older age, longer hypertension duration, diabetes mellitus, and obesity (BMI > 27.5 kg/m2) were significantly associated with RHT.
  • Therapeutic inertia contributed to uncontrolled blood pressure in 27.8% of cases.

Conclusions:

  • A substantial portion of hypertensive patients experience uncontrolled blood pressure, with resistant hypertension being prevalent.
  • Obesity and diabetes mellitus are significant risk factors for resistant hypertension in this population.
  • Therapeutic inertia plays a notable role in the management of uncontrolled hypertension.
Abstract

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